BAKER BROS. ADVISORS LP
Transaction: 06/03/2026
BUY
Change
+19,226
Price
$19.66
Filing
06/05/2026
Type
BUY
Denali Therapeutics Inc.
DNLI • Biotechnology
$22.28
▼ -0.52 (-2.28%)
Current price
EarningsLatest report: Jun 30, 2026
HIGHER-RISK PROFILECautionConfidence: 70%
Quantitative profile — not an investment recommendation.
Quantitative profile — not an investment recommendation.Methodology
Analysis thesis: Caution is warranted. Recent ratios show weaknesses that may limit returns unless fundamentals improve.
Market Cap
$4.17B
Growth
—
Cash Flow
0/5
Trend
Negative
Evidence
Positive revenue growth · 145.1%Manageable debt level · 0.04Healthy liquidity · 9.16Weak profitability
Financial data as of: Jun 30, 2026, 12:00 AM UTCLast earnings update: Jun 30, 2026, 12:00 AM UTCLast profile update: Aug 12, 2026, 12:39 PM UTC
Company Snapshot
Key valuation, quality, financial strength, momentum and analyst data.
Price$22.28
Change-2.28%
Shares Out187.31M
Market Cap$4.17B
Enterprise Value$3.49B
52W Range12.58 - 27.30
Beta1.00
P/E-8.16
P/S1,157.98
P/B5.00
P/FCF-7.31
EV/Sales968.48
Price$22.28
Change-2.28%
Shares Out187.31M
Market Cap$4.17B
Enterprise Value$3.49B
52W Range12.58 - 27.30
Beta1.00
P/E-8.16
P/S1,157.98
P/B5.00
P/FCF-7.31
EV/Sales968.48
EV/EBITDA-6.67
EV/FCF-6.11
Earnings Yield-12.26%
FCF Yield-13.69%
Dividend Yield0.00%
Gross Margin0.00%
Oper. Margin0.00%
Profit Margin0.00%
Debt/Eq0.04
Current Ratio9.16
Quick Ratio9.16
Target$33.67
Target Upside51.12%
Target Median$34.00
Target Range26.00 - 41.00
Volume1.14M
Avg Volume1.77M
EPS Surprise0.04
Investment DNA
How strong this company looks for long-term investors
53
out of 100
Business Quality
Margins, moat, returns
22/100
Financial Strength
Debt, cash, stability
76/100
Growth Potential
Revenue and expansion
95/100
Price Attractiveness
Cheap or expensive today
80/100
Why this score▼
Positive revenue growth · 145.1%Manageable debt level · 0.04Healthy liquidity · 9.16Weak profitability
Analyst view
Analyst sentiment and price target
Analyst sentiment
Based on 19 analyst votes · 2026-09-05
100/100
Bullish
Bullish
19
Hold
0
Bearish
0
Price Target
2026-08-12
Low
$26.00
Mean
$34.57
Median
$34.00
High
$41.00
Insider Transactions
Recent executive and insider activity
BAKER BROS. ADVISORS LP
Transaction: 06/03/2026
BUY
Change
+19,226
Price
$19.66
Filing
06/05/2026
Type
BUY
BAKER BROS. ADVISORS LP
Transaction: 06/03/2026
BUY
Change
+6,408
Price
Not reported
Filing
06/05/2026
Type
BUY
| Insider | Type | Change | Price | Transaction | Filing |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| BAKER BROS. ADVISORS LP | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| BAKER BROS. ADVISORS LP | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Cook Jennifer E. | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Cook Jennifer E. | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Van Hauwermeiren Timothy | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Van Hauwermeiren Timothy | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Thornberry Nancy | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Thornberry Nancy | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Schenkein David P | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Schenkein David P | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Krognes Steve E. | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Krognes Steve E. | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Klein Peter S | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| Klein Peter S | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| FLATLEY JAY T | BUY | +19,226 | $19.66 | 06/03/2026 | 06/05/2026 |
| FLATLEY JAY T | BUY | +6,408 | Not reported | 06/03/2026 | 06/05/2026 |
| Chin Peter Scott | OTHER | 0 | Not reported | 04/10/2026 | 04/21/2026 |
| Chin Peter Scott | OTHER | +43,000 | $22.31 | 04/10/2026 | 04/20/2026 |
| Chin Peter Scott | OTHER | 0 | Not reported | 04/10/2026 | 04/20/2026 |