Turtle Cameron
Transaction: 08/03/2026
SELL
Change
-16
Price
$97.46
Filing
08/05/2026
Type
SELL
Spyre Therapeutics, Inc.
SYRE • Biotechnology
$88.98
▲ +1.73 (+1.98%)
Current price
EarningsLatest report: Jun 30, 2026
WEAK PROFILEWeakConfidence: 70%
Quantitative profile — not an investment recommendation.
Quantitative profile — not an investment recommendation.Methodology
Analysis thesis: Weak historical ratio profile. The current evidence does not support a favorable risk/reward view.
Market Cap
$7.54B
Growth
—
Cash Flow
0/5
Trend
Negative
Evidence
Manageable debt level · 0Healthy liquidity · 13.25Negative growth trendWeak profitability
Financial data as of: Jun 30, 2026, 12:00 AM UTCLast earnings update: Jun 30, 2026, 12:00 AM UTCLast profile update: Aug 6, 2026, 12:35 PM UTC
Company Snapshot
Key valuation, quality, financial strength, momentum and analyst data.
Price$88.98
Change1.98%
Shares Out84.73M
Market Cap$7.54B
Enterprise Value$6.39B
52W Range14.51 - 108.14
Beta3.02
P/E-42.14
P/S83.31
P/B6.85
P/FCF-36.05
EV/Sales70.66
Price$88.98
Change1.98%
Shares Out84.73M
Market Cap$7.54B
Enterprise Value$6.39B
52W Range14.51 - 108.14
Beta3.02
P/E-42.14
P/S83.31
P/B6.85
P/FCF-36.05
EV/Sales70.66
EV/EBITDA-34.46
EV/FCF-30.58
Earnings Yield-2.37%
FCF Yield-2.77%
Dividend Yield0.00%
Gross Margin0.00%
Oper. Margin0.00%
Profit Margin0.00%
Debt/Eq0.00
Current Ratio13.25
Quick Ratio13.25
Target$106.92
Target Upside20.16%
Target Median$117.50
Target Range49.00 - 130.00
Volume1.04M
Avg Volume1.32M
EPS Surprise-0.08
Investment DNA
How strong this company looks for long-term investors
28
out of 100
Business Quality
Margins, moat, returns
22/100
Financial Strength
Debt, cash, stability
70/100
Growth Potential
Revenue and expansion
20/100
Price Attractiveness
Cheap or expensive today
20/100
Why this score▼
Manageable debt level · 0Healthy liquidity · 13.25Negative growth trendWeak profitability
Analyst view
Analyst sentiment and price target
Analyst sentiment
Based on 13 analyst votes · 2026-09-04
96/100
Bullish
Bullish
12
Hold
1
Bearish
0
Price Target
2026-08-06
Low
$49.00
Mean
$105.36
Median
$112.00
High
$135.00
Insider Transactions
Recent executive and insider activity
⚠ 1 high-volume insider sell detected
Burrows Scott L
Transaction: 08/03/2026
SELL
Change
-100
Price
$97.10
Filing
08/05/2026
Type
SELL
Burrows Scott L
Transaction: 08/03/2026
SELL
Change
-7,500
Price
$14.50
Filing
08/05/2026
Type
SELL
| Insider | Type | Change | Price | Transaction | Filing |
|---|---|---|---|---|---|
| Turtle Cameron | SELL | -16 | $97.46 | 08/03/2026 | 08/05/2026 |
| Burrows Scott L | SELL | -100 | $97.10 | 08/03/2026 | 08/05/2026 |
| Burrows Scott L | SELL | -7,500 | $14.50 | 08/03/2026 | 08/05/2026 |
| Turtle Cameron | SELL | -590 | $88.91 | 07/01/2026 | 07/02/2026 |
| Sloan Sheldon | SELL | -1,834 | $88.34 | 07/01/2026 | 07/02/2026 |
| Sloan Sheldon | SELL | -8,334 | $27.46 | 07/01/2026 | 07/02/2026 |
| Burrows Scott L | SELL | -1,725 | $88.37 | 07/01/2026 | 07/02/2026 |
| Burrows Scott L | SELL | -7,500 | $14.50 | 07/01/2026 | 07/02/2026 |
| Burrows Scott L | SELL | -10,000 | $87.14 | 06/25/2026 | 06/26/2026 |
| Burrows Scott L | SELL | -15,000 | $14.50 | 06/25/2026 | 06/26/2026 |
| Fairmount Funds Management LLC | SELL | -16,667 | Not reported | 06/23/2026 | 06/23/2026 |
| Fairmount Funds Management LLC | SELL | -4,684,781 | $85.31 | 06/23/2026 | 06/23/2026 |
| HENDERSON MICHAEL THOMAS | SELL | -20,000 | $100.00 | 06/22/2026 | 06/23/2026 |
| Sloan Sheldon | SELL | -8,333 | $75.00 | 06/03/2026 | 06/03/2026 |
| Sloan Sheldon | SELL | -8,333 | $27.46 | 06/03/2026 | 06/03/2026 |
| Burrows Scott L | SELL | -3,100 | $72.06 | 06/01/2026 | 06/03/2026 |
| Burrows Scott L | SELL | -7,500 | $14.50 | 06/01/2026 | 06/03/2026 |
| Turtle Cameron | SELL | -3,294 | $71.38 | 06/01/2026 | 06/03/2026 |
| Milligan Sandra | BUY | +8,026 | $72.51 | 05/27/2026 | 05/29/2026 |
| McKenna Mark C. | BUY | +8,026 | $72.51 | 05/27/2026 | 05/29/2026 |