BERTHELSEN SPENCER R
Transaction: 07/15/2026
SELL
Change
-5,220
Price
Not reported
Filing
07/17/2026
Type
SELL
Ionis Pharmaceuticals, Inc.
IONS • Biotechnology
$58.09
▼ -0.04 (-0.07%)
Current price
EarningsLatest report: Jun 30, 2026
WEAK PROFILEWeakConfidence: 70%
Quantitative profile — not an investment recommendation.
Quantitative profile — not an investment recommendation.Methodology
Analysis thesis: Weak historical ratio profile. The current evidence does not support a favorable risk/reward view.
Market Cap
$8.67B
Growth
8.8%
Cash Flow
1/5
Trend
Volatile
Evidence
Healthy liquidity · 3.83High debt level · 5.35Negative growth trendWeak profitability
Financial data as of: Jun 30, 2026, 12:00 AM UTCLast earnings update: Jun 30, 2026, 12:00 AM UTCLast profile update: Aug 5, 2026, 2:27 PM UTC
Company Snapshot
Key valuation, quality, financial strength, momentum and analyst data.
Price$58.09
Change-0.07%
Shares Out165.42M
Market Cap$8.67B
Enterprise Value$8.23B
52W Range40.03 - 86.74
Beta0.37
P/E-15.35
P/S9.92
P/B19.71
P/FCF-15.42
EV/Sales9.42
Price$58.09
Change-0.07%
Shares Out165.42M
Market Cap$8.67B
Enterprise Value$8.23B
52W Range40.03 - 86.74
Beta0.37
P/E-15.35
P/S9.92
P/B19.71
P/FCF-15.42
EV/Sales9.42
EV/EBITDA1.92
EV/FCF-14.63
Earnings Yield-6.52%
FCF Yield-6.49%
Dividend Yield0.00%
Gross Margin98.31%
Oper. Margin-40.47%
Profit Margin-40.36%
Debt/Eq5.35
Current Ratio3.83
Quick Ratio3.81
Revenue 5Y8.77%
Target$90.67
Target Upside56.09%
Target Median$89.50
Target Range61.00 - 115.00
Volume2.77M
Avg Volume2.75M
EPS Surprise0.29
Investment DNA
How strong this company looks for long-term investors
29
out of 100
Business Quality
Margins, moat, returns
22/100
Financial Strength
Debt, cash, stability
58/100
Growth Potential
Revenue and expansion
27/100
Price Attractiveness
Cheap or expensive today
20/100
Why this score▼
Healthy liquidity · 3.83High debt level · 5.35Negative growth trendWeak profitability
Analyst view
Analyst sentiment and price target
Analyst sentiment
Based on 33 analyst votes · 2026-09-04
79/100
Bullish
Bullish
19
Hold
14
Bearish
0
Price Target
2026-07-31
Low
$69.00
Mean
$92.83
Median
$89.50
High
$115.00
Insider Transactions
Recent executive and insider activity
BERTHELSEN SPENCER R
Transaction: 07/15/2026
BUY
Change
+5,220
Price
Not reported
Filing
07/17/2026
Type
BUY
HERMAN JOAN E
Transaction: 07/15/2026
SELL
Change
-5,220
Price
Not reported
Filing
07/17/2026
Type
SELL
| Insider | Type | Change | Price | Transaction | Filing |
|---|---|---|---|---|---|
| BERTHELSEN SPENCER R | SELL | -5,220 | Not reported | 07/15/2026 | 07/17/2026 |
| BERTHELSEN SPENCER R | BUY | +5,220 | Not reported | 07/15/2026 | 07/17/2026 |
| HERMAN JOAN E | SELL | -5,220 | Not reported | 07/15/2026 | 07/17/2026 |
| HERMAN JOAN E | BUY | +5,220 | Not reported | 07/15/2026 | 07/17/2026 |
| HANTSON LUDWIG | BUY | +3,399 | Not reported | 07/15/2026 | 07/17/2026 |
| Reikes Peter N | BUY | +3,399 | Not reported | 07/15/2026 | 07/17/2026 |
| Kordasiewicz Holly B. | SELL | -362 | $84.30 | 07/07/2026 | 07/09/2026 |
| Diaz Allene M. | SELL | -10,111 | $47.11 | 07/07/2026 | 07/09/2026 |
| Diaz Allene M. | SELL | -10,111 | $85.42 | 07/07/2026 | 07/09/2026 |
| BENNETT C FRANK | SELL | -15,000 | Not reported | 07/07/2026 | 07/09/2026 |
| BENNETT C FRANK | SELL | -15,000 | $85.46 | 07/07/2026 | 07/09/2026 |
| BERTHELSEN SPENCER R | BUY | +5,369 | $79.19 | 07/01/2026 | 07/06/2026 |
| BERTHELSEN SPENCER R | BUY | +2,301 | Not reported | 07/01/2026 | 07/06/2026 |
| Diaz Allene M. | BUY | +5,369 | $79.19 | 07/01/2026 | 07/06/2026 |
| Diaz Allene M. | BUY | +2,301 | Not reported | 07/01/2026 | 07/06/2026 |
| Hayden Michael R | BUY | +5,369 | $79.19 | 07/01/2026 | 07/06/2026 |
| Hayden Michael R | BUY | +2,301 | Not reported | 07/01/2026 | 07/06/2026 |
| KLEIN JOSEPH III | SELL | -11,518 | $39.94 | 07/01/2026 | 07/06/2026 |
| KLEIN JOSEPH III | BUY | +2,301 | Not reported | 07/01/2026 | 07/06/2026 |
| KLEIN JOSEPH III | SELL | -11,419 | $79.04 | 07/01/2026 | 07/06/2026 |